With a plethora of weight loss supplements on the market, choosing the best diet pill can seem like an overwhelming task. Between the myriad appetite suppressants, fat burners, and prescription diet pills available, the options seem endless.
In this guide, we’ve reviewed the best weight loss pills on the market to see which products actually live up to the hype. Each of the top diet pills below were evaluated on a variety of factors, including ingredients, dosage, benefits, price, user reviews, and refund policy.
Whether you’re embarking on a new weight loss journey or simply striving to shed those last few pounds to reach your target weight, the weight loss supplements listed below are an excellent starting point.
Best Weight Loss Pills on the Market
- PhenQ: Best weight loss supplement overall
- Capsiplex Burn: Best diet pills for men
- PrimeShred: Best for bodybuilding
- Leanbean: Best fat burner for women
- PhenGold: Best for appetite suppression
- Ozemra: Best alternative to semaglutide injections
#1. PhenQ: Best Weight Loss Supplement Overall
PhenQ is our choice for the best weight loss pill of 2023. PhenQ is an effective weight loss supplement that targets 5 areas of metabolic health to help shed fat, reduce cravings, and support natural energy levels.
PhenQ is a popular and effective weight loss supplement from the well-established Wolfson Brands (UK) Limited, which has been in the industry for over ten years.
How Does PhenQ Work?
For people struggling to lose weight and stubborn body fat, PhenQ is one of the best diet pills on the market. It’s so effective because it contains an ingredient called α-Lacys Reset, a combination of alpha-lipoic acid, cysteine, and magnesium that can help you burn fat and lose weight. PhenQ is also a thermogenic fat burner that aids your weight loss in five different ways:
Burns Stubborn Fat – PhenQ helps burn stored fat using thermogenic ingredients such as α-Lacys Reset and capsimax powder. These powerful thermogenic compounds help you burn more calories per day, even while sleeping or resting!
Stabilizes Mood – PhenQ supports cognitive function and balances your mood to combat the mental fatigue that often accompanies dieting.
Limits Fat Production – PhenQ includes effective weight loss ingredients that may reduce the body’s ability to store new fat cells.
Curbs Cravings – PhenQ improves your body’s insulin sensitivity to knock out those cravings for carbs and sweets. It’s also an effective appetite suppressant.
Increases Energy – This thermogenic fat burner gives you a boost of sustained energy by increasing your metabolic rate.
Formula and Ingredients
The PhenQ formula is the key to how these weight loss pills work:
- α-Lacys Reset
- Calcium carbonate
- Chromium picolinate – Curbs cravings
- L-Carnitine fumarate – Burns excess body fat for energy
- Caffeine
- Nopal cactus fiber – Suppresses your appetite
- Capsimax Blend (caffeine, capsicum fruit extract, niacin, black pepper fruit extract) – Assists with thermogenesis and fat burning
- Cellulose (capsule)
How effective is PhenQ? Scientists who performed a study of α-Lacys Reset found that the people who took the ingredient had significant weight loss compared to those who received a placebo pill that didn’t contain α-Lacys Reset. Here are the results:
- A 3.8% increase in overall lean muscle mass
- A 7.24% reduction in body fat
- A 3.44% decrease in body weight
Who Is This Product Best for?
PhenQ is the best weight loss pill for anyone that’s struggling to lose weight with diet and exercise alone. PhenQ is a well-rounded diet pill that attacks weight loss from multiple angles, making it a great option for men and women alike.
- Best weight loss pills on the market
- Helps reduce fat accumulation for a slimmer body
- Crushes cravings, making it easier to stick to any diet plan
- Boosts metabolism for an accelerated weight loss journey
- Balances mood and energy levels
- Manufactured in GMP-approved facilities
- Free shipping
- Huge discounts when buying more than 1 bottle
- 60-day money back guarantee
- Natural alternative to prescription weight loss medication
Click Here for the Lowest Price on PhenQ
#2. Capsiplex Burn: Best Fat Burner for Men
BURN by Capsiplex is a dual-targeting supplement that stimulates weight loss results while promoting improved fitness. By boosting your metabolic rate, Capsiplex BURN helps your body shed unwanted fat, keeping you energized to achieve the physique of your dreams.
In any Capsiplex BURN review, you’ll find large claims about how the supplement can help burn fat and preserve muscles by curbing your cravings, improving your energy, and kicking your metabolism into high gear. But are they true? The company’s all-natural formula filled with powerful herbs and vitamins combined with FDA-approved safe manufacturing practices speaks for itself.
Benefits
Capsiplex BURN can help you achieve your dream physique by targeting six key aspects of weight loss and fitness. The supplement:
- Ignites metabolism: Your metabolism controls how quickly your body converts food into energy. Speeding up your metabolism can shed fat faster and eat more calories while losing weight.
- Burns fat: BURN supplements include proven fat-burning ingredients that help you melt off stubborn areas of unwanted fat.
- Boosts energy: Dieting and exercise often leave you fatigued, but BURN includes energy-boosting ingredients so you can feel motivated while losing weight.
- Reduces cravings: BURN nourishes your body with key supplements that naturally curb cravings.
- Preserves muscle mass: Cutting calories often means losing your hard-earned muscle progress, but BURN ensures you maintain lean muscle mass.
- Improves workout results: BURN helps you feel more energized for successful muscle-building workouts.
Formula Overview
Any Capsiplex BURN review would be incomplete without mentioning its jam-packed formula. Capsiplex BURN features 13 clinically proven ingredients:
- L-Tyrosine: Increases thyroid hormone secretion to balance metabolic rates and boosts dopamine and adrenaline synthesis to improve motivation and focus
- L-Arginine HCL amino acid: Increases nitric acid levels to improve workout recovery rates and boosts growth hormone responses to enhance fat loss and muscle growth results
- InnoSlim® (ginseng and astragalus): Regulates blood sugar levels and speeds up how your body burns through fat
- Caffeine: Boosts lipolysis for faster fat burning and improves workout energy levels
- Capsicum fruit extract: Boosts fat metabolism, allowing your body to shed weight faster
- Green tea leaf extract: Reduces your body’s bad cholesterol for improved cardiovascular health and weight loss
- Black pepper fruit extract: Improves the formula’s bioavailability, allowing you to absorb more of the helpful ingredients
- Green coffee extract: Reduces fat absorption rates and regulates glucose and lipid metabolism levels
- Iodine: Aids in thyroid hormone synthesis, improving metabolic rates and energy
- Chromium: Suppresses hunger cues, allowing you to stick to your diet
- Vitamins B3, B6, and B12: Improves energy, eliminates fatigue, stabilizes moods, and more
How To Use
Capsiplex recommends taking BURN on an empty stomach about 30 minutes before your exercise routine or 30 minutes before breakfast on rest days. The recommended dosage is three capsules with a full glass of water. After taking the capsules, you should feel energized and ready for your workout.
Capsiplex recommends taking the dosage daily for a few months to see full results. You should feel energized immediately, noticing the increased fat-burning effects after a few weeks.
BURN’s key features include the following:
- A transparent ingredient label
- Free shipping on all orders
- Gluten-free capsules
- 60-day money-back guarantees
- Discounts on bulk orders
- FDA-approved manufacturing facilities
- Science-backed ingredients
- Convenient payment options
- Secure online checkouts
Capsiplex BURN is best for active men who need support in their cutting cycles. The formula accelerates fat loss while promoting gym results, allowing men to lose weight while protecting their muscle gains.
Click Here for the Lowest Price on Capsiplex Burn
#3. PrimeShred: Best for Bodybuilding
PrimeShred is the best weight loss supplement on our list for men, although bodybuilders and weight lifters will particularly enjoy its benefits. The manufacturers of PrimeShred, Muscle Club Limited, have a good reputation and many satisfied customers who have tried their dietary supplements and experienced great results.
How Does PrimeShred Work?
PrimeShred works in three different ways to help you lose weight and burn fat while still providing your body with the fuel to build muscle. Here are the three primary ways these diet pills work. They:
1. Kickstart Lipolysis
If you didn’t know, lipolysis is the process of your body breaking down fat and using it for energy. PrimeShred activates the fat-burning hormones and enzymes that trigger lipolysis, helping you to eliminate stubborn fat. It also contains capsaicin, a natural fat burner that can help you target stubborn belly fat by activating hormones in your abdominal area.
2. Speed Up Fat Loss
PrimeShred also helps people lose weight fast by increasing the body’s metabolic rate. Even if you’re at rest, you can still burn fat for energy if your metabolism is high enough. Plus, it helps your body turn your daily calorie intake directly into energy rather than storing the calories as fat cells.
3. Boost Energy and Strengthens Focus
If you’ve ever gone on a low-cal diet, you know that it can make you feel exhausted both physically and mentally. PrimeShred combats those feelings of fatigue, providing you with an energy boost and premium nootropics for increased focus and mental clarity.
In addition, PrimeShred has ingredients that reduce stress while elevating and enhancing your mood. Losing weight can be difficult, and having that extra mental clarity will help you think logically about making healthy lifestyle choices rather than being ruled by your emotions.
Formula and Ingredients
PrimeShred is one of the best weight loss supplements due to its exclusive formula, containing all-natural ingredients that promote fat burning 24/7. Here is the list of the ingredients you’ll find in PrimeShred:
- Caffeine anhydrous
- Cayenne pepper
- Bioperine (black pepper fruit extract)
- Rhodiola Rosea root (adaptogenic herb)
- L-theanine
- Vitamin B complex
- L-tyrosine
- Green coffee bean extract
- DMAE (organic compound)
- Green tea extract
Who Is This Product Best For?
PrimeShred is the best weight loss pill for men that want to shred fat, get lean, and transform their body. It’s a great fat burner if you want to break through frustrating plateaus and strip off those last pounds of stubborn fat.
- Best weight loss pills for men
- Burn stubborn fat without losing energy or muscle mass
- Optimizes your body’s natural fat burning process
- Amplifies your energy and mental focus
- Great for boosting metabolism
- 100-day money back guarantee
- Clinically-backed ingredients
- Vegetarian and vegan-friendly ingredients
Click Here for the Lowest Price on PrimeShred
#4. Leanbean: Best Appetite Suppressant for Women
Leanbean is the best thermogenic fat burner on our list for women and is from the bright minds at Ultimate Life, LTD, in the U.K.
How Does Leanbean Work?
Leanbean uses a combination of low-stimulant alternatives, thermogenic ingredients, and dietary fiber to provide weight loss benefits for women. Studies have shown compelling evidence that women have more trouble than men at avoiding the temptation of hunger cravings. In light of this, manufacturers of this diet pill created it to work with women’s metabolisms as it acts as an appetite suppressant. You should combine Leanbean with a low-fat diet and regular exercise for the best possible results.
Here’s a deeper explanation of how Leanbean helps you lose excess weight and burn stubborn body fat. This product:
1. Eliminates Fatigue
Leanbean protects against fatigue-inducing deficiencies with an exclusive vitamin complex. It also provides a clean energy boost to help you power through your day and your most strenuous workouts.
2. Reduces Food Cravings
Leanbean is a highly effective appetite suppressant, using the dietary fiber glucomannan to keep you feeling full between meals. In addition, this helps you reduce your calorie intake to prevent weight gain and help you lose weight faster.
3. Supports Normal Fat Metabolism
As a thermogenic fat burner, Leanbean supports a normal fat metabolism, helping your body break down fat rather than storing it.
Formula and Ingredients
Leanbean is one of the best all-natural diet pills for women because its formula contains clinically proven ingredients for weight loss. So if you’re having trouble reaching your fitness goals concerning fat loss and overall health, Leanbean can be the extra oomph you need to break past those plateaus.
Are you curious about the exact ingredients in Leanbean? Here’s what you’ll find in this fat burner for women:
- Choline (vital nutrient)
- Glucomannan
- Chromium picolinate (trace mineral)
- Turmeric (stimulant alternative)
- Zinc
- Vitamins B6 and B12
- Green coffee beans
- Chloride (electrolyte)
- Acai berry
- Garcinia Cambogia
- Piperine (black pepper)
Who Is This Product Best for?
Leanbean is the best weight loss supplement for women that want to burn fat, suppress appetite, and boost energy levels. With a 3,000 mg dose of glucomannan, Leanbean should help you feel fuller for longer and make it easier to reduce your calorie intake.
- Natural weight loss pills for women
- Breaks down stored fat to be used for energy
- Helps curb appetite and reduces cravings
- Helps you lose weight faster when combined with low calorie diet
- Money-back guarantee
- Effective weight loss pill for boosting metabolism naturally
- Cutting edge ingredients with no harmful stimulants
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#5. PhenGold: Best Metabolism Booster
Swiss Research Labs Ltd. is the manufacturer of PhenGold, another popular weight loss pill that features clinically proven ingredients and a maximum strength formula. PhenGold is the best prescription weight loss pill alternative on the market.
How Does PhenGold Work?
PhenGold is a weight loss pill with a dedicated customer base of satisfied users that have experienced great results by combining this supplement with exercise and a healthy diet. The ingredients in PhenGold have clinical research backing up their effectiveness regarding weight loss, which is why this fat burner is so popular: it works. The manufacturers used a comprehensive approach to help you lose weight by targeting the main contributors to weight gain.
1. Halts Hunger Cravings
PhenGold diet pills work with caffeine and capsaicin acting as natural appetite suppressants, stopping those pesky snack attacks and hunger cravings right in their tracks. In addition, the formula contains natural mood boosters to reduce stress levels and curtail emotional eating.
2. Activates Fat-Burning Hormones
Your body contains specific hormones that break down and burn fat. PhenGold’s ingredients activate these hormones, increasing the fat-burning process within your body for the best possible results.
3. Increases Your Metabolic Rate
PhenGold is an effective metabolism booster that increases the speed at which your body burns fat and calories. Even when you’re at rest, the formula burns calories using carbohydrates for energy instead of storing them for fat.
4. Improves Motivation and Mood
These diet pills are full of all-natural mood enhancers, helping you stay motivated and feel good about yourself while you embark on your weight loss journey.
5. Boosts Energy and Focus
Everyday life can leave you feeling fatigued, and dieting can make it even worse. Luckily, PhenGold gives you a natural energy boost from green coffee and green tea extract throughout the day.
Formula and Ingredients
The ingredients in PhenGold make it one of the best all-natural diet pills on today’s market. The formula is full of scientifically proven ingredients to help you lose weight and accomplish your fitness goals more quickly.
The ingredients in PhenGold can:
- Boost metabolism
- Increase energy
- Burn stubborn body fat
- Enhance and balance your mood
- Improve focus and mental clarity
- Curb food cravings
Here’s a breakdown of the formula:
- Caffeine
- DMAE (organic compound)
- Vitamin B complex
- Cayenne pepper
- L-tyrosine
- Rhodiola Rosea
- L-theanine
- Green tea extract
- Green coffee beans
Key Features
The manufacturers of PhenGold offer some great selling points for these popular weight loss pills. Here’s a list of the key features of PhenGold:
- Secure checkout and worldwide shipping
- No subscription fees; one-time purchase only
- 100-day money-back guarantee
- Vegetarian- and vegan-friendly product
- Non-GMO ingredients
- Dairy-, soy-, and gluten-free product
Who Is This Product Best for?
PhenGold is a highly effective appetite suppressant, making it an ideal choice for people that struggle with food cravings. It also has caffeine and other mood-enhancing ingredients, which is perfect for anyone that needs a little extra kick to get through the day.
Click Here for the Lowest Price on PhenGold
#6. Ozemra: Best Alternative to Semaglutide Injections
Ozemra is a groundbreaking weight loss supplement developed by VitaGX, a UK-based biotech company. This innovative stack was purposefully created to mirror the effects of prescription weight loss medications such as Ozempic, Saxenda, and WeGovy, all without the need for a prescription and minus the associated side effect risks.
Benefits of Taking Ozemra
Incorporating Ozemra into your daily regimen yields numerous benefits:
Appetite Suppression: Ozemra curbs appetite, promotes prolonged satiety, maintains stable blood sugar levels to prevent cravings, snacking, and binge eating—all without resorting to prescription weight loss pills!
Boosts Metabolism: Ozemra acts as a highly potent metabolism enhancer, primarily through thermogenesis, increasing the resting metabolic rate.
Stops Fat Storage: Ingredients in Ozemra work together to slow down fat accumulation, especially in stubborn, hard-to-shift fat stores like the thighs and abdomen.
Burns Abdominal Fat: The Calcium L-5-Methyltetrahydrofolate in Ozemra has been clinically proven to help reduce overall body fat and to specifically target abdominal fat stores in the process.
Boosts Energy Levels: Ozemra provides a steady, clean energy boost from the precision-dosed, ultra-pure caffeine anhydrous. This allows you to stay focused and train with intensity while dieting.
Enhances Workout Performance: The ALA in Ozemra has been found to preferentially shuttle blood glucose to your muscles and away from fat stores. This gives your muscles more energy during workouts and helps stop fat accumulation.
Formula Overview
Ozemra’s superiority among weight loss supplements is attributed to its advanced formula, comprising the following key ingredients:
- Calcium L-5-Methyltetrahydrofolate Powder (600 mcg): Clinically proven to reduce body fat, especially in abdominal areas.
- Vitamin B12 Premix (100 mcg): Vital in supporting various metabolic processes.
- Chromium Picolinate Powder (200 mcg): Helps maintain stable blood sugar levels.
- Chromium Nicotinate Glycinate Chelate (200 mcg): Supports optimal blood sugar control.
- L-Carnitine L-Tartrate Powder (200 mg): Facilitates the utilization of fatty acids for fuel.
- Alpha-Lipoic Acid (100 mg): Promotes muscle retention, workout performance, and glucose redirection away from fat storage.
- Caffeine Anhydrous USP Powder (100 mg): Precisely dosed to reduce appetite, elevate metabolism, and enhance energy levels without causing side effects.
- Cayenne Pepper Powder (100 mg): Induces thermogenesis, contributing to increased fat loss.
- Glucomannan (250 mg): An exceptional natural appetite suppressant, reducing hunger and preventing overeating.
Each ingredient in Ozemra was meticulously selected for its unique fat-loss properties that synergize with the mechanisms of other ingredients. This synergy empowers Ozemra to deliver results that surpass the sum of its individual components. Moreover, it retains its status as a 100% natural fat burner and appetite suppressant available over the counter.
Ingredients in Ozemra have been proven to deliver:
- A 5.5lb reduction in body weight over 8 weeks (source)
- An up to 28% reduction in fat mass (source)
- A 1.27kg loss of weight, with most from abdominal fat (source)
Ozemra serves as an ideal choice for individuals committed to their weight loss journey and seeking an extra boost. It’s a perfect fit if you’re struggling to adhere to a diet, maintain energy levels, or maximize the benefits of your workouts.
Pros
- Non-Prescription and Natural: Ozemra is a 100% natural weight loss supplement and appetite suppressant available without a prescription.
- Comprehensive Weight Loss Approach: It addresses various weight loss pathways, ensuring effective and sustainable results.
- Clinically Supported Ingredients: Ozemra incorporates ingredients backed by clinical research, underscoring its effectiveness.
- Energy Boost: In addition to appetite suppression, it provides an energy boost, promoting an active lifestyle.
Cons
- Cost Consideration: Ozemra may come with a higher price tag compared to some conventional appetite suppressants.
- Availability: Availability may vary due to its specialized nature.
Click Here for the Lowest Price on Ozemra
How to Choose The Best Weight Loss Supplements
Active Ingredients
When choosing the best weight loss pills, the first thing to consider is the active ingredients. Common ingredients in some of the best weight loss pills include caffeine and green tea extract, which are often found in thermogenic fat burners designed to help with weight management. Some ingredients, like Garcinia Cambogia, are marketed to help reduce body weight by suppressing appetite. Verify that these active ingredients are supported by peer-reviewed research, and compare them to prescription weight loss medications if applicable.
Dosage
Dosage can be a critical factor in your weight loss process. Some pills may require multiple doses throughout the day, while others might be a one-time daily supplement. Be sure that you’re comfortable with the dosage regimen. Prescription medications for weight loss usually have a well-researched dosage schedule; make sure any supplement you choose has similar rigor behind its dosage recommendations.
Avoid Proprietary Formulas
Avoid products that use proprietary blends. This lack of transparency can make it difficult to assess how effective the product may be for weight management. Always opt for products that list the amount of each active ingredient so you can compare them to prescription weight loss medications if needed.
Brand Reputation
Brand reputation is vital when it comes to choosing a weight loss pill to help manage excess weight. Look for companies that are well-known, transparent, and have positive reviews from users and experts alike. Verify that the product is manufactured in a facility that follows Good Manufacturing Practices (GMP).
Side Effects
It’s essential to consider the potential side effects of a weight loss pill. Common side effects may include jitters, heart palpitations, or digestive issues. If you have pre-existing medical conditions like high blood pressure, consult your healthcare provider to minimize risk. Some prescription medications for weight loss have well-studied side effect profiles, which can serve as a point of comparison.
Price
Price is a crucial factor in your weight loss journey. However, a higher price doesn’t always equate to higher quality or effectiveness in shedding excess weight. Compare prices relative to the number of servings, the quality of ingredients, and the credibility of the brand. Some lower-priced options may be as effective as more expensive prescription medications for weight loss.
Refund Policy
A robust refund policy can provide added assurance in your weight loss process. Look for companies that offer a money-back guarantee if you’re not satisfied with the product. This not only shows that the company believes in its product but also allows you to try the pill with less financial risk.
Remember, there is no one-size-fits-all solution to weight loss. Supplements should be used in conjunction with a balanced diet and regular exercise for effective weight management. And most importantly, consult a healthcare provider for a full medical evaluation before starting any new supplement or prescription medications, especially if you have underlying conditions like high blood pressure.
Best Weight Loss Medications
Prescription weight loss drugs are medications that are used to help individuals lose weight when lifestyle changes such as diet and exercise have not been successful on their own. These medications are typically prescribed by a healthcare provider to people with a body mass index (BMI) of 30 or greater, or those with a BMI of 27 or greater who also have weight-related health problems such as type 2 diabetes or high blood pressure.
Naltrexone-Bupropion (Contrave)
Contrave is an FDA-approved weight loss medication combining naltrexone, used for addiction treatment, with bupropion, an antidepressant. Designed for weight management, it targets the central nervous system to suppress appetite and manage body weight. Used in adults with a BMI of 30 or more, or 27 with weight-related conditions, it should complement lifestyle changes for obesity treatment. Possible side effects include nausea and an increase in blood pressure, necessitating monitoring.
Liraglutide (Saxenda)
Saxenda, an injectable GLP-1 receptor agonist with FDA approval for weight management, helps regulate calorie intake by inducing satiety. It is a prescription drug for those struggling with weight gain and is effective when used with a calorie-restricted diet and exercise. Saxenda has been shown to lower body weight but can lead to gastrointestinal disturbances and should be used with caution in individuals with a personal or family history of certain thyroid cancers.
Orlistat (Xenical and Alli)
Orlistat, available as Xenical and Alli, is an FDA-approved anti-obesity medication that reduces the absorption of fat to aid in weight loss. It is recommended for those with a BMI of 30 or more, or 27 with obesity-related conditions, and should be taken along with a low-fat diet to minimize calorie intake and prevent weight gain. While effective, it can cause gastrointestinal side effects and requires vitamin supplementation due to reduced fat absorption.
Semaglutide (Wegovy, Ozempic)
Semaglutide, with FDA approval under the names Wegovy for weight management and Ozempic for blood sugar control in type 2 diabetes, aids in reducing body weight by enhancing feelings of fullness. As a once-weekly injectable prescription drug, it’s intended for individuals with a BMI over 30, or over 27 with weight-related conditions. It not only helps in weight loss but may also improve blood sugar levels, although gastrointestinal side effects are common.
Phentermine (Adipex, Suprenza)
Phentermine, an FDA-approved prescription drug for short-term use, helps suppress appetite as part of a weight management program. Brand names like Adipex and Suprenza facilitate weight loss by reducing hunger and are intended for obese individuals when exercise and calorie restriction are insufficient to prevent weight gain. Side effects can include a rise in blood pressure and heart rate, so it’s often prescribed for a few weeks to reduce risks.
Phentermine-Topiramate (Qsymia)
Qsymia is an FDA-approved weight loss drug combining phentermine and topiramate for long-term weight management. It’s prescribed to reduce body weight in adults with a BMI of 30 or more, or 27 with comorbidities, as part of an obesity treatment plan that includes a reduced-calorie diet and physical activity. Patients should monitor for side effects like dizziness and changes in taste sensation. Due to topiramate’s teratogenic effects, it’s essential for women of childbearing age to use contraception while on Qsymia.
Best Natural OTC Supplements for Weight Loss
Glucomannan
Glucomannan is a dietary fiber isolated from the konjac plant. It’s a popular appetite suppressant that absorbs water and forms a gel-like mass in your stomach. As it takes longer to pass through your digestive system, you’ll feel fuller for longer and have fewer cravings and hunger pangs.
It promotes diet adherence and reduces the average number of calories you eat daily, speeding up weight loss and making it easier to stay on track. Studies show that glucomannan is effective at promoting weight loss in overweight individuals and has the added benefit of lowering blood sugar and blood cholesterol levels while combating constipation, a common benefit of dietary fiber.
Green Tea Extract
Green tea extract contains several different ingredients that may promote fat burning, including caffeine, catechins, and antioxidants. Caffeine is a known stimulant and thermogenic compound that also assists appetite suppression, while catechins increase fat oxidation and help maintain a stable body weight after fat loss.
Several studies show that green tea extract can increase fat burning and may even be able to target belly fat. However, green tea does contain large amounts of caffeine, which may make it unsuitable for individuals who dislike the jittery feeling of excessive stimulant use, especially when the supplement has other sources of caffeine.
Chromium or Chromium Picolinate
Chromium is an essential mineral that assists insulin in its function of regulating blood sugar levels. Being an essential mineral means that your body can’t produce it, so you need to obtain it through your diet. Since your body only absorbs approximately 2.5% of the chromium you eat, a severely limited diet may lower chromium levels, resulting in poor insulin response and fatigue.
Cayenne Pepper
Cayenne pepper extract contains capsaicin, the compound responsible for the burning feeling associated with eating chilis and peppers. Capsaicin is a thermogenic compound that may aid in boosting metabolism and reducing appetite. It also enhances fat oxidation, meaning that your body can burn fat faster, supplying you with energy while helping you lose weight. Even better, the enhanced fat oxidation can help you maintain your new weight after you’ve reached your goal.
L-Carnitine
Many of the best weight loss pills on the market contain L-Carnitine. L-carnitine is an amino acid that plays a vital role in energy production in cells. Since L-carnitine plays an important role in fatty acid metabolism, research has examined how supplementation affects weight loss in humans.
While some studies show promise, other results are mixed due to poor sample selection and controls, and more rigorous research is necessary to discover how effective carnitine is at promoting fat loss.
Green Coffee Extract
Green coffee extract is a popular ingredient in many of the best weight loss pills. Green coffee extract contains several compounds that may assist in weight loss, including caffeine and chlorogenic acid. The roasting process significantly affects chlorogenic acid levels, which is why most natural fat-burning supplements contain unroasted green coffee beans.
Several small-scale studies show that green coffee bean extract is moderately successful in improving weight loss outcomes in overweight individuals, but further research is essential in determining how effective this compound is, especially compared to simply using caffeine.
Caffeine Anhydrous
Caffeine is one of the most popular ingredients in the best weight loss supplements due to its established effectiveness as a metabolism booster and appetite suppressant. Caffeine can boost your basal metabolic rate by up to 11%, and some studies show that it may increase your body’s fat-burning capability by 29%.
It also acts as a stimulant and can provide the energy you need to power through tough workouts, which is especially useful if you’re dieting and have a severe calorie deficit. However, be careful of diet pills that combine ingredients such as green tea extract, green coffee bean extract, and caffeine, as these will have much more caffeine than your average cup of coffee.
Forskolin
Forskolin is a compound found in mint that may stimulate fat oxidation by raising cAMP levels in cells in rats. Current research is limited to two small-scale studies that offer conflicting results. While it shows promise, further research is necessary to determine whether it’s an effective compound that assists in human weight loss.
Conjugated Linoleic Acid
Conjugated linoleic acid is a common ingredient found in many of the best weight loss supplements on the market. Conjugated linoleic acid is a fatty acid found in meat and dairy products that has potential weight loss benefits. It inhibits insulin signaling, preventing the body from absorbing blood sugars, reducing caloric intake, and burning excess fat. A metastudy of current research shows that CLA has a modest impact on weight loss in humans that may not be worth the adverse side effects associated with the supplement.
The same studies that showed CLA’s effect on weight loss also showed that CLA increased inflammation and raised levels of liver enzymes, indicating possible liver damage.
Frequently Asked Questions
Which weight loss medications are FDA approved?
The FDA-approved weight loss medications include orlistat (Xenical, Alli), phentermine (Adipex, Suprenza), phentermine-topiramate (Qsymia), naltrexone-bupropion (Contrave), liraglutide (Saxenda), and semaglutide (Wegovy). These prescription drugs are intended for individuals with certain criteria related to body mass index (BMI) and weight-related health issues.
What are weight loss supplements?
Weight loss supplements are products designed to support weight loss efforts. They often contain a blend of herbs and other organic compounds that claim to increase metabolism, reduce appetite, or improve the body’s ability to burn fat.
Do weight loss pills really work?
The effectiveness of weight loss supplements varies widely. Some may offer modest weight loss benefits when combined with a healthy diet and regular exercise, while others may not have any significant impact. It’s important to have realistic expectations and understand that supplements alone are not a magic solution for weight loss.
When should I consider anti-obesity medications?
Consider anti-obesity medications if you have a BMI of 30 or higher, or a BMI of 27 or higher with weight-related health conditions such as type 2 diabetes, high blood pressure, or sleep apnea, and if you haven’t been able to achieve weight loss through diet and exercise alone. These medications should be part of a comprehensive lifestyle treatment plan under a healthcare provider’s supervision. Always discuss with your doctor to ensure they are a suitable option.
What ingredients should I look for in the best supplements for weight loss?
Common ingredients in weight loss supplements include caffeine, green tea extract, conjugated linoleic acid (CLA), garcinia cambogia, and glucomannan. Each has different purported mechanisms for aiding weight loss.
How do I choose the best supplements to help lose weight?
Look for weight loss supplements with ingredients that have some backing from scientific research. It’s also important to choose products from reputable manufacturers and check for third-party testing to ensure quality and safety.
Do prescription weight loss drugs have any side effects?
Yes, prescription weight loss drugs can have side effects ranging from mild to severe, including increased heart rate, high blood pressure, insomnia, gastrointestinal disturbances, and anxiety. Some may cause dependency or withdrawal symptoms upon discontinuation. The severity and type of side effects vary depending on the medication and the individual. It’s crucial to discuss potential risks with a healthcare provider and to be monitored regularly while taking any weight loss medication.
Summary of the Best Diet Pills for Weight Loss
- PhenQ: Best weight loss supplement overall
- Capsiplex Burn: Best diet pills for men
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